smiA [2017-06-07 16:51:42]

swarming motility inhibitor A, adaptor protein for LonA-mediated degradation of SwrA

locus: BSU35319

pI: 4.00

mw: 15.00 kDa

protein length: 125 aa

gene length: 375 bp

function: control of swarming motility

product: adaptor protein for LonA-mediated degradation of SwrA

essential: no

synonyms: yvzG

Genomic Context

categories

• [category|SW 4|Lifestyles] → [category|SW 4.1|Exponential and early post-exponential lifestyles] → [category|SW 4.1.1|Motility and chemotaxis] → [category|SW 4.1.1.1|Signal transduction in motility and chemotaxis] → [category|SW 4.1.1.1.5|Additional chemotaxis signal transduction and regulatory proteins]

Gene

Coordinates: 3,631,763 → 3,632,140

Phenotypes of a mutant

• presence of predifferentiated swarmer cells in liquid medium [Pubmed|25538299]
• A mutation in ''smiA'' suppresses the motility defect of a ''[gene|6A21293823151C6980BF52B31A4B249A8440F2E1|lytC]'' mutant [Pubmed|19542270]

Expression and Regulation

Operons

• genes: [gene|4DBF4635B5C5A7541E8F97440D139DAA02547B99|yvyC]-[gene|C6012DEA301DF5B2DDD7E673A736BD3E5163F209|fliD]-[gene|4882FAD988FEDD0E72E4CAFB10C8DE61DDAC23B0|fliS]-[gene|4DE156D248FAF7DE3ED9AC35F006B5319A3C1BDA|fliT]-[gene|A6E7212D159F076F5D26F9C02F340B40C3667623|smiA]-[gene|06FEA5F205B40DD5CF8D9F1328E940D4543F4741|S1350]-[gene|37B8B671B84266A7D65B90A9077A0DFF458D1851|hpf]
  description: [pubmed|22383849]

  sigma factors

  • [protein|7024E4162A6D827069F882FDEACA696EBC05DD40|SigD]: sigma factor, [Pubmed|26577401], in [regulon|7024E4162A6D827069F882FDEACA696EBC05DD40|SigD regulon]

Biological materials

Mutant

• available in the [SW|Daniel Kearns] lab

Labs working on this gene/protein

• [SW|Daniel Kearns], Indiana University, Bloomington, USA, [http://www.bio.indiana.edu/facultyresearch/faculty/Kearns.html homepage]

References

• 19542270,25538299,26577401